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JoVE Journal
Genetics

This content is Open Access.

基于纠错 DNA 和 RNA 测序的稀有事件检测方法
 

基于纠错 DNA 和 RNA 测序的稀有事件检测方法

Article doi: 10.3791/57509
August 3rd, 2018 Usage Statistics

Summary August 3rd, 2018

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下一代测序 (0.5–2.0%) 是基因组特征的有力工具, 受平台高错误率的限制。我们描述了我们的错误纠正排序方法, 使我们能够避免的误差率和检测突变的变异等位基因分数罕见的0.0001。

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