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Um pequeno modelo Animal de perfusão de fígado normotérmica Ex Vivo
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Um pequeno modelo Animal de perfusão de fígado normotérmica Ex Vivo

Article DOI: 10.3791/57541-v • 08:32 min • June 27th, 2018
June 27th, 2018 •
1,2, 1, 1,2, 1,2, 1, 1, 3, 4, 2, 1,3, 1,2
1Collaboration for Organ Perfusion, Protection, Engineering and Regeneration (COPPER) Lab, Division of Transplant, Department of Surgery, Comprehensive Transplant Center, Ohio State University Wexner Medical Center, 2Department of Surgery, Division of Transplant, Ohio State University Wexner Medical Center, 3Department of Surgery, Division of CardioThoracic Surgery, Ohio State University Wexner Medical Center, 4Department of Medicine, Ohio State University Wexner Medical Center

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Há uma escassez de doadores de fígado significativo, e expandiram-se critérios para doadores de fígado. Normotérmica ex vivo fígado perfusão (NEVLP) foi desenvolvido para avaliar e modificar a função do órgão. Este estudo demonstra um modelo do rato de NEVLP e testa a capacidade do peguilado-catalase, para atenuar a lesão hepática de preservação.

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Medicina edição 136 normotérmico ex vivo da perfusão hepática NEVLP marginal os órgãos estendido doadores de critérios roedores rato pequeno modelo animal,
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