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Um modelo de cardiomiopatia induzida por doxorrubicina no Zebrafish adulto
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Um modelo de cardiomiopatia induzida por doxorrubicina no Zebrafish adulto

Article DOI: 10.3791/57567-v • 08:09 min • June 7th, 2018
June 7th, 2018 •
*1,2,3, *2,3, 2,3,4, 1,2,3
1Clinical and Translational Sciences Track, Mayo Clinic Graduate School of Biomedical Sciences, 2Department of Biochemistry and Molecular Biology, Mayo Clinic, 3Division of Cardiovascular Diseases, Mayo Clinic, 4Institute of Life Science, Beijing University of Chinese Medicine
* These authors contributed equally

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Um método para gerar um modelo de cardiomiopatia induzida pela doxorrubicina em adulto peixe-zebra (Danio rerio) é descrito aqui. Apresentam-se duas formas alternativas de injeção intraperitoneal e condições para reduzir as variações entre diferentes grupos experimentais são discutidas.

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Medicina edição 136 doxorrubicina cardiomiopatia fase aguda fase crônica zebrafish injeção intraperitoneal modelo de doença
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