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Molekylær analyse av Endothelial-mesenchymal overgang av omforming vekst faktor-β signalisering
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Molekylær analyse av Endothelial-mesenchymal overgang av omforming vekst faktor-β signalisering

Article DOI: 10.3791/57577-v • 07:49 min • August 3rd, 2018
August 3rd, 2018 •
1, 2,3, 4, 2
1David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 2Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, 3Hastings Center for Pulmonary Research, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, 4Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo

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En protokoll for i vitro induksjon av endothelial-mesenchymal overgang (EndMT), som er nyttig for å undersøke mobilnettet signalveier involvert i EndMT, er beskrevet. I denne eksperimentelle modellen er EndMT indusert av behandling med TGF-β i MS-1 endotelceller.

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Biologi problemet 138 Endothelial-mesenchymal overgangen EndMT endothelial celle TGF-β α-SMA kollagen microRNA
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