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Molekylær analyse af endotel-mesenchymale overgang induceret af Transforming Growth Factor-β signalering
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Molekylær analyse af endotel-mesenchymale overgang induceret af Transforming Growth Factor-β signalering

Article DOI: 10.3791/57577-v • 07:49 min • August 3rd, 2018
August 3rd, 2018 •
1, 2,3, 4, 2
1David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 2Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, 3Hastings Center for Pulmonary Research, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Keck School of Medicine, University of Southern California, 4Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo

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En protokol til in vitro- induktion i endothelial-mesenchymale overgang (EndMT), som er nyttige for efterforskningen cellulær signalering veje involveret i EndMT, er beskrevet. I denne eksperimentelle model, er EndMT foranlediget af behandling med TGF-β i endothelial celler, MS-1.

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Biologi spørgsmålet 138 Endothelial-mesenchymale overgang EndMT endotel celle TGF-β α-SMA kollagen mikroRNA
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