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Journal / Genetics / Gene candidato teste em estudos de coorte clínica …
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JoVE Journal Genetics
Gene candidato teste em estudos de coorte clínica com genotipagem multiplexada e espectrometria de massa
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Gene candidato teste em estudos de coorte clínica com genotipagem multiplexada e espectrometria de massa

Article DOI: 10.3791/57601-v • 05:53 min • June 21st, 2018
June 21st, 2018 •
1,2, 2,3, 2,3,4, 2,3,5
1Molecular Genetics of Chronic Inflammation and Allergic Disease, Max-Delbrück Center for Molecular Medicine, 2Murdoch Childrens Research Institute, 3Department of Paediatrics, University of Melbourne, 4Centre for Social and Early Emotional Development, Faculty of Health, Deakin University, 5Department of Paediatrics, University of Western Australia

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Identificação de variantes genéticas contribuindo para doenças humanas complexas nos permite identificar novos mecanismos. Aqui, vamos demonstrar uma abordagem de genotipagem multiplex de genes candidatos ou análise de percurso de gene que maximiza a cobertura de baixo custo e é passível de estudos de coorte-baseado.

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Genética edição 136 genotipagem ensaio multiplex espectrometria de massa MALDI-TOF gene candidato coorte clínica
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