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Kandidaten-Gen Tests in klinischen Kohortenstudien mit gemultiplexten Genotypisierung und Massenspektrometrie
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Kandidaten-Gen Tests in klinischen Kohortenstudien mit gemultiplexten Genotypisierung und Massenspektrometrie

Article DOI: 10.3791/57601-v • 05:53 min • June 21st, 2018
June 21st, 2018 •
1,2, 2,3, 2,3,4, 2,3,5
1Molecular Genetics of Chronic Inflammation and Allergic Disease, Max-Delbrück Center for Molecular Medicine, 2Murdoch Childrens Research Institute, 3Department of Paediatrics, University of Melbourne, 4Centre for Social and Early Emotional Development, Faculty of Health, Deakin University, 5Department of Paediatrics, University of Western Australia

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Identifizierung von Genvarianten, die einen Beitrag zur komplexen menschlichen Krankheit ermöglicht neuartige Mechanismen zu identifizieren. Hier zeigen wir einen Multiplex-Genotypisierung Ansatz Kandidatengene oder Weg Genanalyse, die maximiert die Reichweite bei niedrigen Kosten und Kohorte-Studien zugänglich ist.

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Ausgabe 136 Genotypisierung Multiplex-Assays Genetik MALDI-TOF-Massenspektrometrie Kandidaten-gen klinische Kohorte
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