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Journal / Neuroscience / Amiloid β mevduat matris yardımlı lazer…
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Neuroscience

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JoVE Journal Neuroscience
Amiloid β mevduat matris yardımlı lazer desorpsiyon/iyonlaşma kütle spektrometresi Imaging ile insan beynindeki görselleştirme
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Amiloid β mevduat matris yardımlı lazer desorpsiyon/iyonlaşma kütle spektrometresi Imaging ile insan beynindeki görselleştirme

Article DOI: 10.3791/57645-v • 09:31 min • March 7th, 2019
March 7th, 2019 •
*1, *2, 1, 1, 1, 3, 4
1Department of Life and Medical Systems, Doshisha University, 2Bruker Daltonics K.K., 3The Brain Bank for Aging Research, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 4Graduate School of Brain Science, Doshisha University
* These authors contributed equally

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Moleküler görüntüleme matris yardımlı lazer desorpsiyon/iyonlaşma tabanlı görüntüleme kütle spektrometresi (maldı-IMS) ile birden çok analitler eş zamanlı haritalama biyolojik örnekleri sağlar. Burada, Alzheimer hastalığı ve serebral amiloid angiopathy örnekleri maldı-IMS kullanarak beyin dokuları algılama ve görselleştirme amiloid β protein için bir iletişim kuralı mevcut.

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Neuroscience sayı: 145 maldı-görüntüleme kütle spektrometresi insan otopsi beyin amiloid β Alzheimer hastalığı Senil plaklar serebral amiloid angiopathy
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