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Protocol to Create Chronic Wounds in Diabetic Mice
 

Protocol to Create Chronic Wounds in Diabetic Mice

Article DOI: 10.3791/57656-v 06:55 min September 25th, 2019
September 25th, 2019

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Summary

Chronic wounds are developed from acute wounds on a diabetic mouse model by inducing high levels of oxidative stress after a full-thickness cutaneous wound. The wound is treated with inhibitors for catalase and glutathione peroxidase, resulting in impaired healing and biofilm development by bacteria present in the skin microbiome.

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Chronic Wounds Diabetic Mice Mouse Model Wound Chronicity Medical Field Protocol Hair Clippers Depilatory Lotion Skin Reaction
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