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Protokol til at skabe kroniske sår i diabetiske mus
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Protokol til at skabe kroniske sår i diabetiske mus

Article DOI: 10.3791/57656-v • 06:55 min • September 25th, 2019
September 25th, 2019 •
1, 1
1Department of Molecular, Cell and Systems Biology, University of California, Riverside

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Kroniske sår er udviklet fra akutte sår på en diabetisk musemodel ved at inducerende høje niveauer af oxidativt stress efter en fuld-tykkelse kutane sår. Såret er behandlet med hæmmere for katalase og glutathion peroxidase, hvilket resulterer i nedsat heling og biofilm udvikling af bakterier til stede i hudens mikrobiome.

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Medicin sårheling kronisk sår nedsat heling diabetisk fodsår oxidativt stress biofilm
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