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In Vivo Nanovector Lieferung von einem Herz-spezifische MicroRNA-Schwamm
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In Vivo Nanovector Lieferung von einem Herz-spezifische MicroRNA-Schwamm

Article DOI: 10.3791/57845-v • 09:53 min • June 15th, 2018
June 15th, 2018 •
1, 2, 2
1Princess Margaret Cancer Centre, University of Toronto, 2Department of Pathology, Department of Cardiology, Johns Hopkins University

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Gewebe-spezifische MicroRNA-Hemmung ist eine Technologie, die im Feld MicroRNA unterentwickelt ist. Hier beschreiben wir ein Protokoll, um erfolgreich die MiR-181 MicroRNA-Familie in Myoblast Zellen aus dem Herzen zu hemmen. Nanovector-Technologie wird verwendet, um eine MicroRNA Schwamm zu liefern, die erhebliche in Vivo Cardio-spezifische MiR-181 Familie Hemmung zeigt.

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Biologie Ausgabe 136 MicroRNA MiRNA MiRNA-Schwamm MiRNA Hemmung Nanopartikel Nanovector MiR-181 Herz mitochondriale miRNA
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