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Journal / Neuroscience / 微粒相关α synuclein…
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Neuroscience

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JoVE Journal Neuroscience
微粒相关α synuclein 聚合体对原代神经元的外源性管理--纤维形成的强大细胞模型
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微粒相关α synuclein 聚合体对原代神经元的外源性管理--纤维形成的强大细胞模型

Article DOI: 10.3791/57884-v • 09:16 min • June 26th, 2018
June 26th, 2018 •
1,2, 1, 1
1Bio@SNS Laboratory, Scuola Normale Superiore, 2International School for Advanced Studies (SISSA/ISAS)

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本协议的目标是提供一个基于细胞的系统,在体内复制α synuclein 聚合体的形成。细胞内阿尔法-synuclein 包裹体的种子在原代神经元的内化和传播的外源管理的原生微粒相关的阿尔法-synuclein 集分离的病阿尔法 synuclein 转基因小鼠。

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神经科学 问题 136 α synuclein 聚集 微粒 原发性神经元 帕金森氏病 细胞模型。
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