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Cancer Research

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JoVE Journal Cancer Research
Live celle avbildning av den TGF-β/Smad3 signalnettverk Pathway In Vitro og i Vivo bruker en Adenovirus Reporter System
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Live celle avbildning av den TGF-β/Smad3 signalnettverk Pathway In Vitro og i Vivo bruker en Adenovirus Reporter System

Article DOI: 10.3791/57926-v • 11:06 min • July 30th, 2018
July 30th, 2018 •
*1, *1, 1, 1
1Department of Surgery (RMH), University of Melbourne
* These authors contributed equally

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Her presenterer vi en protokoll for levende celle imaging TGF-β/Smad3 signalnettverk aktivitet ved hjelp av en adenovirus reporter system. Systemet sporer transcriptional aktivitet i sanntid og kan brukes til både enkeltceller i vitro og i levende dyrmodeller.

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Kreftforskning problemet 137 TGF-β live celle bildebehandling adenovirus celle signalisere bryst kreft Smad3 transcriptional aktivisering
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