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JoVE Journal Cancer Research
Multimodal en bioluminescerende og Positron-emissions-tomografi/edb tomografi billeddannelse af myelomatose knoglemarv Xenografts i NOG mus
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Multimodal en bioluminescerende og Positron-emissions-tomografi/edb tomografi billeddannelse af myelomatose knoglemarv Xenografts i NOG mus

Article DOI: 10.3791/58056-v • 05:32 min • January 7th, 2019
January 7th, 2019 •
1, 2, 3, 3, 1,3, 4, 1, 1,3
1Greater Los Angeles Veteran Administration Healthcare System, 2San Diego Veterans Administration Healthcare System, 3University of California, Los Angeles, 4Perkin Elmer

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Her bruger vi en bioluminescerende, X-ray, og positron-emissions-tomografi/beregnet tomografi imaging til at studere hvordan hæmmende mTOR aktivitet påvirker knoglemarven-aflægger myelomatose tumorer i en xenograft model. Dette giver mulighed for fysiologisk relevante, ikke-invasiv og multimodale analyser af den anti-myelomatose effekt på terapier målretning knoglemarv-aflægger myelomatose tumorer i vivo.

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Kræftforskning spørgsmålet 143 myelomatose xenografts bioluminescence PET/CT tumor mikromiljø knoglemarv
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