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Journal / Immunology and Infection / Valutazione delle risposte a cellula T Zika…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Valutazione delle risposte a cellula T Zika Virus-specifici in organi di nuova di Ifnar1 infetti- / - Mice
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Valutazione delle risposte a cellula T Zika Virus-specifici in organi di nuova di Ifnar1 infetti- / - Mice

Article DOI: 10.3791/58110-v • 10:01 min • October 17th, 2018
October 17th, 2018 •
*1,2, *2, *3, 1,2, 4, 2, 5, 6, 3, 1,2,4,6, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Medical Virology and Viral Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, 4Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, 5Laboratory Animal Center, Chinese Center for Disease Control and Prevention, 6CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences
* These authors contributed equally

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Un protocollo per valutare le risposte delle cellule T antigene-specifiche negli organi nuova di Ifnar1- / - modello murino per l'infezione del virus (ZIKV) di Zika è descritto. Questo metodo è fondamentale per indagare i meccanismi cellulari della protezione e immunopatogenesi di vaccini ZIKV ed è inoltre utile per la loro valutazione di efficacia.

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Immunologia e infezione numero 140 virus di Zika cellule di T antigene-specifiche vaccinazione nuova organi tetramero
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