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En Proximal kultur metod att studera parakrin signalering mellan celler
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En Proximal kultur metod att studera parakrin signalering mellan celler

Article DOI: 10.3791/58144-v • 08:17 min • August 28th, 2018
August 28th, 2018 •
1, 1, 1, 2, 1,3,4
1Indiana University School of Medicine, 2Urology, Indiana University Health Southern Indiana Physicians, 3Indiana University Melvin and Bren Simon Cancer Center, 4Department of Medical and Molecular Genetics, Indiana University School of Medicine

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Parakrin och juxtacrine cellulära interaktioner har en viktig roll i många biologiska processer, inklusive tumör progression, immunsvar, angiogenes och utveckling. Här, en proximal kultur metoden används för att studera parakrin signalering där lokaliserade koncentrationerna av de utsöndrade faktorerna upprätthålls samtidigt förhindra cellulära direktkontakt.

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Biologi fråga 138 parakrin signalering utsöndras faktor konditionerat medium receptor ligand exosomes mikromiljö
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