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JoVE Journal Immunology and Infection
Kvantificering af Efferocytosis af encellede Fluorescens mikroskopi
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Kvantificering af Efferocytosis af encellede Fluorescens mikroskopi

Article DOI: 10.3791/58149-v • 06:15 min • August 18th, 2018
August 18th, 2018 •
1, 1, 2,3, 1
1Department of Microbiology and Immunology and the Center for Human Immunology, University of Western Ontario, 2Institute of Infection and Global Health, University of Liverpool, 3Department of Respiratory Research, Aintree University Hospital NHS Foundation Trust

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Efferocytosis, fagocyterende fjernelse af apoptotiske celler, er forpligtet til at opretholde homøostase og lettes ved receptorer og signalering veje, der giver mulighed for anerkendelse, engulfment og internalisering af apoptotiske celler. Heri, præsenterer vi en Fluorescens mikroskopi protokol til kvantificering af efferocytosis og aktivitet af efferocytic signaling veje.

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Immunologi og infektion spørgsmålet 138 Efferocytosis fagocytose apoptose mikroskopi phagocyt makrofag
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