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Indução de ateroma através da ativação de receptores de mineralocorticoide em camundongos deficientes em Apolipoprotein E

Article DOI: 10.3791/58303-v • 07:36 min • September 26th, 2018
September 26th, 2018 •
1, 1, 1, 1, 1,2
1Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele Pisana, Rome, Italy, 2Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy

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Descreveremos um protocolo para induzir a aterosclerose na raiz da aorta de ApoE- / - ratos alimentados com uma dieta aterogênico, através de uma contínua liberação de aldosterona. Também são descritos métodos para caracterizar a composição da placa bacteriana.

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Medicina edição 139 aterosclerose aldosterona inflamação ApoE- / - raiz aórtica imuno-histoquímica
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