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JoVE Journal Behavior
Angst stress-Enhanced Learning, een robuuste knaagdier Model van Posttraumatische Stress-Stoornis
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Angst stress-Enhanced Learning, een robuuste knaagdier Model van Posttraumatische Stress-Stoornis

Article DOI: 10.3791/58306-v • 05:49 min • October 13th, 2018
October 13th, 2018 •
1,2, 1,2, 1,2,3
1Department of Psychology, University of California, Los Angeles, 2Staglin Center for Brain and Behavioral Health, University of California, Los Angeles, 3Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles

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Hier beschrijven we de gedetailleerde methodologie vereiste stress-enhanced angst leren (SEFL) experimenten, een preklinische model van posttraumatische stress-stoornis, in zowel de ratten en muizen. Het model maakt gebruik van aspecten van Pavlov angst conditionering en bevriezing als een index van verbeterde angst in knaagdieren.

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