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Journal / Developmental Biology / Een cel-gebaseerde Assay te onderzoeken…
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Developmental Biology

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JoVE Journal Developmental Biology
Een cel-gebaseerde Assay te onderzoeken niet-spier Myosin II Contractility via de gevouwen-gastrulatie signalering traject in Drosophila S2R + cellen
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Een cel-gebaseerde Assay te onderzoeken niet-spier Myosin II Contractility via de gevouwen-gastrulatie signalering traject in Drosophila S2R + cellen

Article DOI: 10.3791/58325-v • 07:15 min • August 19th, 2018
August 19th, 2018 •
1, 1, 2, 2, 2, 2, 1,3,4, 2
1Department of Biology, The University of North Carolina at Chapel Hill, 2Department of Biology, Reed College, 3Carolina Center for Genome Sciences, The University of North Carolina at Chapel Hill, 4Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill

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Hier beschrijven we een test van de contractility met behulp van Drosophila S2R + cellen. De toepassing van een exogene ligand, gevouwen gastrulatie (Fog), leidt tot het activeren van de mist signalering traject en mobiele contractility. Deze test kan worden gebruikt om te onderzoeken van de regulering van cellulaire contractility eiwitten in de mist signalering traject.

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Ontwikkelingsbiologie kwestie 138 apicale vernauwing mist signalering cellulaire contractility niet-spier myosin II actine signalering
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