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Journal / Chemistry / Automatisering av en fantes et Positron-utslipp…
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Chemistry

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JoVE Journal Chemistry
Automatisering av en fantes et Positron-utslipp tomografi (PET) Radiotracer syntese protokoll for klinisk produksjon
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Automatisering av en fantes et Positron-utslipp tomografi (PET) Radiotracer syntese protokoll for klinisk produksjon

Article DOI: 10.3791/58428-v • 10:20 min • October 26th, 2018
October 26th, 2018 •
*1, *2,3, 2,4, 1, 2,3, 2,4
1SOFIE, 2Department of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles (UCLA), 3Ahmanson Translational Imaging Division, University of California, Los Angeles (UCLA), 4Crump Institute for Molecular Imaging, University of California, Los Angeles (UCLA)
* These authors contributed equally

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Fantes et positron-utslipp tomografi (PET) tenkelig nettsteder som er involvert i flere tidlig klinisk forskning prøvelser trenger robuste og allsidig radiotracer produksjon evner. Bruke radiotracer [18F] BSA eksempel vi illustrerer hvordan du kan automatisere syntesen av en radiotracer med en fleksibel, kassett-baserte radiosynthesizer og validere syntese for klinisk bruk.

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Kjemi problemet 140 fantes et Positron-utslipp tomografi automatisert radiosynthesis klinisk validering ELIXYS BSA klinisk nytte radiotracer
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