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palt1 副酶活性对髓系先天信号通路的调控
 
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palt1 副酶活性对髓系先天信号通路的调控

Article DOI: 10.3791/58439-v 07:09 min January 7th, 2019
January 7th, 2019

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Summary

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alt1 调节先天免疫, 但这种情况是如何发生的仍未确定。我们使用选择性 malt1 副囊酶抑制剂 mlt-827 来解开 malt1 对 toll 样或 c 型凝集素受体下游的先天信号的贡献, 证明 malt1 调节骨髓细胞因子的产生, 并在下游c 型乳素样受体, 选择性的。

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生物学 第143期 alt1 副适应酶 dectin mincle toll 样受体 蛋白酶抑制 髓质细胞 cbm 复合体
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