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JoVE Journal
Bioengineering

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全完整型小鼠软骨外种机械负荷对软骨细胞损伤的实时可视化与分析
 
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全完整型小鼠软骨外种机械负荷对软骨细胞损伤的实时可视化与分析

Article DOI: 10.3791/58487-v 08:42 min January 7th, 2019
January 7th, 2019

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Summary

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我们提出了一种方法来评估细胞损伤死亡的空间程度后, 完整的小鼠关节关节应用受控机械负荷或冲击。该方法可用于研究骨关节炎、遗传因素和不同的加载方案如何影响原位软骨细胞的脆弱性。

Tags

生物工程 第143期 细胞死亡、软骨细胞、软骨细胞、小鼠模型、静态负荷、撞击、创伤
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