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Journal / Cancer Research / Un modelo con ratones Syngeneic células B linfoma …
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Cancer Research

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JoVE Journal Cancer Research
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Un modelo con ratones Syngeneic células B linfoma de evaluación preclínica de las células de T automóvil CD19

Article DOI: 10.3791/58492-v • 12:16 min • October 16th, 2018
October 16th, 2018 •
1, 1, 1, 1,2, 1
1Manchester Cancer Research Centre Building, Department Cancer Sciences, University of Manchester, 2Celyad

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Aquí, presentamos un protocolo para la producción y los ensayos preclínicos murinas CD19 coche de células de T por transducción retroviral y utilización como terapia contra establecido syngeneic A20 linfoma en ratones BALB/c con o sin lymphodepleting acondicionamiento previo.

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Investigación del cáncer número 140 coche T células camiones T-cell terapia adoptiva syngeneic ratón inmunoterapia modelo A20 IL-12 acondicionamiento previo CD19 linfoma
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