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Journal / Cancer Research / Syngena mus B-cells lymfom modell för preklinisk…
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Cancer Research

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JoVE Journal Cancer Research
Syngena mus B-cells lymfom modell för preklinisk utvärdering av CD19 CAR T-celler
Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
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Capturing Small Molecule Communication Between Tissues and Cells Using Imaging Mass Spectrometry
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Syngena mus B-cells lymfom modell för preklinisk utvärdering av CD19 CAR T-celler

Article DOI: 10.3791/58492-v • 12:16 min • October 16th, 2018
October 16th, 2018 •
1, 1, 1, 1,2, 1
1Manchester Cancer Research Centre Building, Department Cancer Sciences, University of Manchester, 2Celyad

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Här presenterar vi ett protokoll för produktion och prekliniska test av murina CD19 CAR T-celler av retrovirala transduktion och utilization som en terapi mot etablerade syngena A20 B-cells lymfom hos BALB/c-möss med eller utan lymphodepleting förkonditionering.

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Cancer Research fråga 140 bil T celler lastbilar adoptiv T-cell terapi syngena mus modell A20 immunterapi IL-12 förkonditionering CD19 lymfom
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