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JoVE Journal
Cancer Research

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同源小鼠 B 细胞淋巴瘤模型对 CD19 轿车 T 细胞的临床前评价

同源小鼠 B 细胞淋巴瘤模型对 CD19 轿车 T 细胞的临床前评价

Article doi: 10.3791/58492
October 16th, 2018

Summary October 16th, 2018

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在这里, 我们提出了一个协议, 用于生产和临床前测试小鼠 CD19 汽车 T 细胞的逆转录病毒转导和利用, 作为一种治疗同源 A20 B 细胞淋巴瘤在 BALB/c 鼠有或没有 lymphodepleting预调理。

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