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Journal / Cancer Research / 同源小鼠 B 细胞淋巴瘤模型对 CD19 轿车 T…
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Cancer Research

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JoVE Journal Cancer Research
同源小鼠 B 细胞淋巴瘤模型对 CD19 轿车 T 细胞的临床前评价
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同源小鼠 B 细胞淋巴瘤模型对 CD19 轿车 T 细胞的临床前评价

Article DOI: 10.3791/58492-v • 12:16 min • October 16th, 2018
October 16th, 2018 •
1, 1, 1, 1,2, 1
1Manchester Cancer Research Centre Building, Department Cancer Sciences, University of Manchester, 2Celyad

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在这里, 我们提出了一个协议, 用于生产和临床前测试小鼠 CD19 汽车 T 细胞的逆转录病毒转导和利用, 作为一种治疗同源 A20 B 细胞淋巴瘤在 BALB/c 鼠有或没有 lymphodepleting预调理。

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癌症研究 问题 140 汽车 t 细胞 卡车 收养 t 细胞疗法 同源小鼠模型 A20 免疫治疗 IL-12 预调理 CD19 淋巴瘤
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