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Direkta intratekal injektion av rekombinant Adeno-associerade virus i vuxna möss
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Direkta intratekal injektion av rekombinant Adeno-associerade virus i vuxna möss

Article DOI: 10.3791/58565-v • 08:17 min • February 15th, 2019
February 15th, 2019 •
*1, *2, 1, 3, 1,4
1Department of Neurology, Second Hospital of Hebei Medical University, 2No.2 Middle School of Shijiazhuang, 3Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 4Key Laboratory of Hebei Neurology
* These authors contributed equally

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Här presenterar vi en direkt intratekal injektionsteknik med 1% lidokain hydroklorid i en viral lösning att säkerställa effektiv adeno-associerade virus leverans till små djur och etablera ett scoringsystem för att förutsäga transduktion effektivitet i central nervsystemet enligt graden av övergående svaghet orsakade av lidokain.

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Neurovetenskap fråga 144 intratekal AAV gen transduktion centrala nervsystemet lidokain hydroklorid andra
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