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JoVE Journal Chemistry
Une nouvelle méthode simple pour la mesure de lipophilie (logP) à l’aide de 19F-RMN
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Une nouvelle méthode simple pour la mesure de lipophilie (logP) à l’aide de 19F-RMN

Article DOI: 10.3791/58567-v • 09:32 min • January 30th, 2019
January 30th, 2019 •
1, 1, 1, 1, 2, 1
1Chemistry, University of Southampton, 2Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca

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Un roman et une simple variante de la méthode de shake-flacon a été développé pour la mesure précise lipophilie de composés fluorés par 19F RMN.

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Chimie numéro 143 lipophilie organofluorés 19F RMN fluoration alcanols fluorés hydrates de carbone
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