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Journal / Neuroscience / Cell-based test per studiare la Clearance di Tau…
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Neuroscience

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JoVE Journal Neuroscience
Cell-based test per studiare la Clearance di Tau anticorpo-mediato da Microglia
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Cell-based test per studiare la Clearance di Tau anticorpo-mediato da Microglia

Article DOI: 10.3791/58576-v • 07:18 min • November 9th, 2018
November 9th, 2018 •
1, 2,3, 3, 3, 4, 3
1Neuroscience Discovery, Janssen Pharmaceutical Company of Johnson & Johnson, Belgium, 2Department of Hematopoiesis, Sanquin Research and Landsteiner Laboratory, The Netherlands, 3Janssen Prevention Center, Janssen Pharmaceutical Company of Johnson & Johnson, The Netherlands, 4Neuroscience Discovery, Janssen Pharmaceutical Company of Johnson & Johnson, Pennsylvania

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Qui descriviamo un'analisi basata sulle celle per valutare quantitativamente l'assorbimento tau da microglia con l'obiettivo di creare uno strumento in fase di sperimentazione per caratterizzare meglio i meccanismi di azione degli anticorpi anti-tau.

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Neuroscienze problema 141 morbo di Alzheimer tauopathy tau aggregazione microglia BV-2 l'assorbimento liquidazione.
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