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JoVE Journal Bioengineering
Protein Kinase C-Delta-Inhibitor Peptid Formulierung mit Gold-Nanopartikeln
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Protein Kinase C-Delta-Inhibitor Peptid Formulierung mit Gold-Nanopartikeln

Article DOI: 10.3791/58741-v • 06:06 min • March 9th, 2019
March 9th, 2019 •
1, 2, 1, 1, 1, 1, 1,3
1Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Respiratory Medicine Research Laboratory, Institute of Translation Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 3Institute of Medical Science, Faculty of Medicine, University of Toronto

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Wir haben mit eine gold-Nanopartikel-Peptid-Hybrid früher intravenös liefern einen synthetischen Peptid, Protein-Kinase C-Delta-Hemmer, die Ischämie-Reperfusion-induzierten akuten Lungenversagen reduziert. Hier zeigen wir das ausführliche Protokoll der Arzneistoff-Formulierung. Anderen intrazellulären Peptide können in ähnlicher Weise formuliert werden.

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Biotechnik Ausgabe 145 Biomaterialien intravenöse Medikamentenabgabe Peptid-Therapeutika Medikament Lieferfahrzeug Aminosäure Arzneistoff-Formulierung
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