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JoVE Journal Bioengineering
Proteína quinase C-delta inibidor do Peptide formulação utilizando nanopartículas de ouro
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Proteína quinase C-delta inibidor do Peptide formulação utilizando nanopartículas de ouro

Article DOI: 10.3791/58741-v • 06:06 min • March 9th, 2019
March 9th, 2019 •
1, 2, 1, 1, 1, 1, 1,3
1Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, 2Respiratory Medicine Research Laboratory, Institute of Translation Medicine, Shanghai General Hospital, Shanghai Jiaotong University, 3Institute of Medical Science, Faculty of Medicine, University of Toronto

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Anteriormente nós usamos um híbrido de peptídeo de nanopartículas de ouro para entregar por via intravenosa um peptídeo sintético, inibidor da proteína quinase C-delta, que reduziu a lesão pulmonar aguda induzida por isquemia-reperfusão. Aqui nós mostramos o protocolo detalhado da formulação da droga. Outros peptídeos intracelulares podem ser formulados da mesma forma.

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Bioengenharia edição 145 biomateriais entrega de drogas intravenosas terapêutica do peptide veículo de entrega de drogas aminoácido formulação de drogas
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