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Journal / Cancer Research / Forberedelse af Exosomes til siRNA levering til…
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Cancer Research

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JoVE Journal Cancer Research
Forberedelse af Exosomes til siRNA levering til kræftceller
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Forberedelse af Exosomes til siRNA levering til kræftceller

Article DOI: 10.3791/58814-v • 09:59 min • December 5th, 2018
December 5th, 2018 •
*1, *1, 1
1Institute of Pharmaceutical Science, King's College London
* These authors contributed equally

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En exosome er en ny generation af drug delivery luftfartsselskaber. Vi etablerede en exosome isolation protokol med højt udbytte og renhed for siRNA levering. Vi har også indkapslet fluorescently mærket uspecifikke siRNA i exosomes og undersøgt den cellulære optagelse af siRNA-loaded exosomes i kræftceller.

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Kræftforskning sag 142 Exosome Isolation karakterisering siRNA levering cellulære optagelse Nanocarrier
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