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In Vitro Kras Assay om aan te tonen van de gevolgen van arsenicum huid cel migratie

Article DOI: 10.3791/58838-v • 09:24 min • February 23rd, 2019
February 23rd, 2019 •
1,4, 1, 1, 1,3, 1,2,4
1Department of Biological Sciences, Northern Arizona University, 2Department of Mechanical Engineering, Northern Arizona University, 3Department of Chemistry and Biochemistry, Northern Arizona University, 4Center for Bioengineering Innovation, Northern Arizona University

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Deze studie richt zich op een in vitro model voor wond genezing (kras assay) als een mechanisme om te bepalen hoe milieu aanwezige contaminanten zoals arsenicum invloed cellulaire migratie. De resultaten tonen aan dat deze in vitro -assay snelle en vroege aanwijzingen van wijzigingen in cellulaire migratie vóór in vivo experimenten biedt.

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Milieuwetenschappen kwestie 144 kras assay cellulaire migratie wondgenezing arseen milieu aanwezige contaminanten menselijke dermale fibroblasten
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