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Journal / Bioengineering / Progettazione di film di silicio poroso come…
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Bioengineering

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JoVE Journal Bioengineering
Progettazione di film di silicio poroso come elementi portanti del fattore di crescita del nervo
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Progettazione di film di silicio poroso come elementi portanti del fattore di crescita del nervo

Article DOI: 10.3791/58982-v • 10:12 min • January 25th, 2019
January 25th, 2019 •
1, 2,3, 2,3, 1,4
1Department of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, 2Faculty of Engineering, Bar-Ilan University, 3Bar-Ilan Institute of Nanotechnologies and Advanced Materials, 4Russell Berrie Nanotechnology Institute, Technion - Israel Institute of Technology

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Qui, presentiamo un protocollo per progettare e fabbricare film nanostrutturati di silicio poroso (PSi) come elementi portanti degradabili per il fattore di crescita del nervo (NGF). Differenziamento neuronale e la conseguenza di PC12 cellule e topi radice dorsale neuroni gangliari (DRG) sono caratterizzati dal trattamento con i vettori di NGF-caricato PSi.

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Bioingegneria numero 143 Nerve Growth Factor silicio poroso PC12 gangli spinali modulata differenziamento neuronale
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