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Journal / Bioengineering / Intra-CARDIAC side-avfyring lys kateter for…
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Bioengineering

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JoVE Journal Bioengineering
Intra-CARDIAC side-avfyring lys kateter for overvåking Cellular metabolisme bruker transmuralt absorbansen spektroskopi av Perfusert pattedyr hjerter
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Intra-CARDIAC side-avfyring lys kateter for overvåking Cellular metabolisme bruker transmuralt absorbansen spektroskopi av Perfusert pattedyr hjerter

Article DOI: 10.3791/58992-v • 08:51 min • May 12th, 2019
May 12th, 2019 •
1,2, 1, 1
1Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, 2Department of Biomedical Engineering, The George Washington University

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Her introduserer vi en metode for å bruke en intra-ventrikkel optisk kateter i perfusert hjerter til å utføre absorbansen spektroskopi over hjertet veggen. Dataene innhentet gir robust informasjon om vev oksygen spenning samt substrat utnyttelse og membran potensial samtidig med CARDIAC ytelse tiltak i denne allestedsnærværende forberedelse.

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Bioteknologi hjertefunksjon hjerte metabolisme mitokondrier myoglobin cytokrom oksidase cytokrom c cytokrom b FAD mitokondrier membran potensial vev oksygenering optisk spektroskopi Spectral montering
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