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Immunology and Infection

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JoVE Journal Immunology and Infection
Um modelo do rato para avaliar a resposta imune inata à infecção de Staphylococcus aureus
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Um modelo do rato para avaliar a resposta imune inata à infecção de Staphylococcus aureus

Article DOI: 10.3791/59015-v • 09:15 min • February 28th, 2019
February 28th, 2019 •
1, 1, 1, 2, 1
1Department of Biomedical Engineering, University of California Davis, 2Department of Dermatology, Johns Hopkins University School of Medicine

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Uma abordagem é descrita para a detecção em tempo real da resposta imune inata de ferimento cutâneo e Staphylococcus aureus infecção de ratos. Por LysM-EGFP comparando os ratos (que possuem fluorescentes neutrófilos) com um LysM-EGFP mestiços cepa de rato imunodeficientes, avançamos nossa compreensão da infecção e o desenvolvimento de abordagens para combater a infecção.

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Imunidade inata Imunologia e infecção edição 144 Staphylococcus aureus os neutrófilos cicatrização de feridas inflamação todo animal imagem
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