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Journal / Bioengineering / A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
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JoVE Journal Bioengineering
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
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A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Article DOI: 10.3791/59034-v • 10:42 min • February 27th, 2019
February 27th, 2019 •
1, 1,2, 1,3, 4,5,6, 1,2,3
1Department of Chemistry, Brooklyn College, The City University of New York, 2Ph.D. Program in Chemistry, The Graduate Center of The City University of New York, 3Ph.D. Program in Biochemistry, The Graduate Center of The City University of New York, 4Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 5Women's Health Research Institute, Icahn School of Medicine at Mount Sinai, 6Laboratory for Translational Research, Western Connecticut Health Network

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Summary
Automatic Translation

This protocol describes an efficient method to synthesize a nanoemulsion of an oleic acids-platinum(II) conjugate stabilized with a lysine-tyrosine-phenylalanine (KYF) tripeptide. The nanoemulsion forms under mild synthetic conditions via self-assembly of the KYF and the conjugate.

Tags

Tripeptide-stabilized Nanoemulsion Oleic Acid Peptide Modification Diagnostic Purposes Anti-cancer Platinum Biodegradable Low Toxicity Stabilizing Agent Pharmaceutical Applications In-vivo Studies Ovarian Cancer Cisplatin Silver Nitrate Hydrochloric Acid Centrifuge Filtrate Platinum Detection Sodium Hydroxide
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