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Journal / Immunology and Infection / Formazione immagine confocal di RNA…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Formazione immagine confocal di RNA Double-Stranded e Pattern Recognition Receptors in infezione Virus RNA negativo
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Formazione immagine confocal di RNA Double-Stranded e Pattern Recognition Receptors in infezione Virus RNA negativo

Article DOI: 10.3791/59095-v • 06:44 min • January 26th, 2019
January 26th, 2019 •
1, 1, 1
1Department of Pathology and Institute for Human Infections and Immunity, University of Texas Medical Branch

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RNA double-stranded prodotto durante la replicazione del virus RNA possa essere riconosciuto dai recettori di riconoscimento di pattern per indurre una risposta immunitaria innata. Per i virus del RNA negativo-senso, l'interazione tra il basso livello dsRNA e PRRs rimane poco chiaro. Abbiamo sviluppato un metodo di microscopia confocale per visualizzare arenavirus dsRNA e PRR in singole celle.

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Immunologia e infezione numero 143 RNA double-stranded virus RNA negativo arenavirus virus di Junin RIG-I MDA-5 recettori di riconoscimento di pattern microscopia confocale
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