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Journal / Immunology and Infection / Konfokal billeddannelse af dobbelt-strenget RNA…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Konfokal billeddannelse af dobbelt-strenget RNA og mønster anerkendelse receptorer i Negative-følelse RNA-virusinfektion
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Konfokal billeddannelse af dobbelt-strenget RNA og mønster anerkendelse receptorer i Negative-følelse RNA-virusinfektion

Article DOI: 10.3791/59095-v • 06:44 min • January 26th, 2019
January 26th, 2019 •
1, 1, 1
1Department of Pathology and Institute for Human Infections and Immunity, University of Texas Medical Branch

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Dobbelt-strenget RNA produceret under RNA-virus replikering kan genkendes af mønster anerkendelse receptorer til at fremkalde en medfødte immunrespons. For negative-følelse RNA-vira uklart, samspillet mellem den laveste-niveau-dsRNA og PRRs. Vi har udviklet en Konfokal mikroskopi metode til at visualisere arenavirus dsRNA og PRR i individuelle celler.

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Immunologi og infektion spørgsmålet 143 dobbelt-strenget RNA negative-følelse RNA-virus arenavirus Junin virus RIG-I MDA-5 mønster anerkendelse receptorer konfokalmikroskopi
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