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Journal / Immunology and Infection / Tek zincir MHC Co-agonism insan CD8 + T hücre…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Tek zincir MHC Co-agonism insan CD8 + T hücre aktivasyonu içinde araştırmak için teknoloji kullanımı
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Journal (Immunology and Infection)
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Journal (Immunology and Infection)
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Tek zincir MHC Co-agonism insan CD8 + T hücre aktivasyonu içinde araştırmak için teknoloji kullanımı

Article DOI: 10.3791/59126-v • 12:09 min • February 28th, 2019
February 28th, 2019 •
1, 1, 1, 1,2, 3, 4, 3, 1,2,5, 6, 1, 1,2,5
1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Immunology Programme, Life Sciences Institute, National University of Singapore, 3Emerging Infectious Diseases Program, Duke-NUS Graduate Medical School, 4Singapore Immunology Network, A*STAR, 5NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, 6Department of Immunology, Wright-Fleming Institute, Imperial College London

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Bu iletişim kuralı açıklar tek zinciri MHC sınıf ı insan CD8 + T hücre aktivasyonu moleküler etkileşimlerde araştırmaya kompleksleri: mühendislik antijen sunan tek zincir ifade hücreleri nesil oluşturur, kültür insan CD8 + T hücre klonu ve T hücre aktivasyonu deneyler.

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İmmünoloji ve enfeksiyon sayı: 144 tek zincir MHC insan T hücre aktivasyonu T hücre Antijen tanıma kendini peptid istikrarlı bir hücre kültürünü mühendislik antijen sunan hücreler PBMC yalıtım insan T hücre degranulation tahlil insan T hücre sitokin üretim
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