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Immunology and Infection

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JoVE Journal Immunology and Infection
En murine model af dengue virus-induceret akut viral encephalitis-lignende sygdom
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En murine model af dengue virus-induceret akut viral encephalitis-lignende sygdom

Article DOI: 10.3791/59132-v • 04:23 min • April 28th, 2019
April 28th, 2019 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3
1Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, 2Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, 3Center of Infectious Disease and Signaling Research, National Cheng Kung University

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Her præsenterer vi en protokol for at skabe en immun kompetent ICR (Institute of Cancer Research) murine model af centralnervesystemet infektion for at vise udviklingen af neuropati. Overvågning af akutte virale encephalitiske lidelser ved identiske sygdoms scorer kan udføres for at vise denguevirus-induceret neuropati in vivo.

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Immunologi og infektion murine dengue virus encephalitis neurotoksicitet intracerebral injektion intraperitoneal injektion patte mus
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