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Journal / Neuroscience / Konvektion Verbesserte Lieferung von…
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JoVE Journal Neuroscience
Konvektion Verbesserte Lieferung von optogenetischen Adeno-assoziierten Viral vektor an den Cortex von Rhesus Macaque unter Anleitung von Online-MRT-Bildern
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Journal (Neuroscience)
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Quantifying the Heterogeneous Distribution of a Synaptic Protein in the Mouse Brain Using Immunofluorescence
Journal (Neuroscience)
Quantifying the Heterogeneous Distribution of a Synaptic Protein in the Mouse Brain Using Immunofluorescence
 
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Konvektion Verbesserte Lieferung von optogenetischen Adeno-assoziierten Viral vektor an den Cortex von Rhesus Macaque unter Anleitung von Online-MRT-Bildern

Article DOI: 10.3791/59232-v • 08:52 min • May 23rd, 2019
May 23rd, 2019 •
1,2, 2,3, 4, 1,2,3,4
1Departments of Bioengineering, University of Washington, 2Washington National Primate Research Center, 3Department of Electrical and Computer Engineering, University of Washington, 4Department of Physiology and Center for Integrative Neuroscience, University of California, San Francisco

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Hier zeigen wir Magnetresonanz (MR)-geführte Konvektions-verstärkte Abgabe (CED) von viralen Vektoren in den Kortex als effizienten und vereinfachten Ansatz zur Erzielung optogenetischer Expression über große kortikale Bereiche im Makakenhirn hinweg.

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Neurowissenschaften Ausgabe 147 Optogenetik Nichtmenschliche Primaten Rhesus-Makaken Virale Vektorabgabe Opsin-Expression Primärer motorischer Kortex Primärs somatosensorischer Kortex
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