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JoVE Journal Neuroscience
A convecção aumentou a entrega do vetor viral adeno-associado Optogenetic ao córtice de Rhesus macaque a orientação de imagens em linha de MRI
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A convecção aumentou a entrega do vetor viral adeno-associado Optogenetic ao córtice de Rhesus macaque a orientação de imagens em linha de MRI

Article DOI: 10.3791/59232-v • 08:52 min • May 23rd, 2019
May 23rd, 2019 •
1,2, 2,3, 4, 1,2,3,4
1Departments of Bioengineering, University of Washington, 2Washington National Primate Research Center, 3Department of Electrical and Computer Engineering, University of Washington, 4Department of Physiology and Center for Integrative Neuroscience, University of California, San Francisco

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Aqui, nós Demonstramos a ressonância magnética (Sr.)-a entrega aumentada da convecção guiada (CED) de vetores virais no córtice como uma aproximação eficiente e simplificada para conseguir a expressão optogenética através das grandes áreas corticais no cérebro do macaque.

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Neurociência edição 147 Optogenética primatas não humanos Rhesus macaques entrega de vetores virais expressão de opsin córtex motor primário córtex somatosensorial primário
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