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Journal / Genetics / 工程神经前体宫内移植,用于Vivo神经结构研究…
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Genetics
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JoVE Journal Genetics
工程神经前体宫内移植,用于Vivo神经结构研究
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工程神经前体宫内移植,用于Vivo神经结构研究

Article DOI: 10.3791/59242-v • 15:00 min • May 11th, 2019
May 11th, 2019 •
1, 1, 1
1Laboratory of Cerebral Cortex Development, SISSA

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该方法基于神经元前体的体外慢病毒工程,将其共同移植到野生型大脑中,并配对对"测试"和"控制"衍生物的形态学评价,从而能够精确建模新皮质的体内基因控制神经元形态,以简单和负担得起的方式。

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遗传学 问题 147 神经元形态学 神经质 基因表达 转基因控制 透镜病毒 室内移植
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