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Neuroscience

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JoVE Journal Neuroscience
Elektroforetiske levering av γ-aminobutyric acid (GABA) i epileptiske Focus hindrer beslag i mus
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Elektroforetiske levering av γ-aminobutyric acid (GABA) i epileptiske Focus hindrer beslag i mus

Article DOI: 10.3791/59268-v • 07:01 min • May 16th, 2019
May 16th, 2019 •
*1,5, *2,3, 1,4, 2,3, 1,5
1Aix Marseille Université, Institut de Neurosciences des Systèmes (INS), 2Electrical Engineering Division, University of Cambridge, 3Department of Bioelectronics, Centre Microélectronique de Provence - Ecole Nationale Supérieure des Mines de Saint-Étienne (CMP-EMSE), 4Institut de Neurosciences de la Timone, Centre National de la Recherche Scientifique (CNRS) UMR 7289 & Aix- Marseille Université, 5Neuroengineering Research Group, Interdisciplinary Excellence Center, Department of Medical Microbiology and Immunobiology, University of Szeged
* These authors contributed equally

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Utfordringen med epilepsi forskning er å utvikle nye behandlinger for pasienter der klassisk terapi er utilstrekkelig. Ved hjelp av en ny protokoll-med hjelp av et implanterbare stoff leveringssystem-vi er i stand til å kontrollere beslag i anesthetized mus ved Elektroforetiske levering av GABA i epileptiske fokus.

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Nevrovitenskap mikrovæskebasert ion pumpe μFIP elektroforese epilepsi beslag epileptiske fokus GABA hippocampus silisium sonde 4-aminopyridin 4AP mus
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