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Journal / Neuroscience / A entrega electrophoretic do ácido γ-aminobutyric …
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Neuroscience

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JoVE Journal Neuroscience
A entrega electrophoretic do ácido γ-aminobutyric (GABA) no foco epileptic impede apreensões nos ratos
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A entrega electrophoretic do ácido γ-aminobutyric (GABA) no foco epileptic impede apreensões nos ratos

Article DOI: 10.3791/59268-v • 07:01 min • May 16th, 2019
May 16th, 2019 •
*1,5, *2,3, 1,4, 2,3, 1,5
1Aix Marseille Université, Institut de Neurosciences des Systèmes (INS), 2Electrical Engineering Division, University of Cambridge, 3Department of Bioelectronics, Centre Microélectronique de Provence - Ecole Nationale Supérieure des Mines de Saint-Étienne (CMP-EMSE), 4Institut de Neurosciences de la Timone, Centre National de la Recherche Scientifique (CNRS) UMR 7289 & Aix- Marseille Université, 5Neuroengineering Research Group, Interdisciplinary Excellence Center, Department of Medical Microbiology and Immunobiology, University of Szeged
* These authors contributed equally

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O desafio da pesquisa da epilepsia é desenvolver tratamentos novos para os pacientes onde a terapia clássica é inadequada. Usando um protocolo novo — com a ajuda de um sistema implantáveis da entrega da droga — nós podemos controlar apreensões em ratos anestesiados pela entrega electrophoretic de GABA no foco epileptic.

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Neurociência edição 147 bomba de íon microfluídico μFIP eletroforese epilepsia apreensão foco epiléptico GABA hipocampo sonda de silício 4-aminopyridina 4AP mouse
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