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JoVE Journal Bioengineering
Crescimento e caracterização de organóides irradiados de glândulas mamárias
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Crescimento e caracterização de organóides irradiados de glândulas mamárias

Article DOI: 10.3791/59293-v • 09:49 min • May 3rd, 2019
May 3rd, 2019 •
1, 1, 1, 1,2,3
1Department of Chemical and Biomolecular Engineering, Vanderbilt University, 2Department of Biomedical Engineering, Vanderbilt University, 3Department of Radiation Oncology, Vanderbilt University Medical Center

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Organóides desenvolvidos a partir de glândulas mamárias do camundongo foram irradiados e caracterizados para avaliar características epiteliais e interações com células imunes. Os organóides irradiados podem ser usados para melhor avaliar as interações célula-célula que podem levar ao recrutamento de células tumorais em tecido normal irradiado.

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BioEngineering cultura organóide 3D glândula mamária resposta normal à radiação tecidual interações celulares câncer de mama Imunologia do câncer
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