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JoVE Journal Neuroscience
Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
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Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

Article DOI: 10.3791/59310-v • 07:03 min • July 31st, 2019
July 31st, 2019 •
1,2, 3, 3, 1
1School of Life Sciences, Guangzhou University, 2Institute for Brain Research and Rehabilitation, South China Normal University, 3School of Life Sciences, South China Normal University

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Summary
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We present in vivo electrophysiological recording of the local field potential (LFP) in bilateral secondary motor cortex (M2) of mice, which can be applied to evaluate hemisphere lateralization. The study revealed altered levels of synchronization between the left and right M2 in APP/PS1 mice compared to WT controls.

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Hemisphere Lateralization Bilateral Local Field Potential Recording Secondary Motor Cortex Mice Interregional Electrophysiology Connectivity Directionality Coupling Electrophysiological Measurement Neuronal Activities Synchronization Of Electrical Signals Alzheimer's Disease Pathogenesis Biomarkers Surgery Anesthesia Depth Stereotaxic Apparatus Ointment Shave The Head Sterilize The Area Incision Forceps Scalp Residual Tissue Clean The Skull Hydrogen Peroxide Coated Cotton Buds Recording Microelectrodes
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