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Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats
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Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats

Article DOI: 10.3791/59327-v • 05:54 min • April 4th, 2019
April 4th, 2019 •
1, 1, 2, 1
1Department of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, 2Department of Orthopaedics, Harvard Medical School - Beth Israel Deaconess Medical Center

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By using an innovative ground-based analogue model, we are able to simulate a space mission including a trip to (0 g) and a stay on Mars (0.38 g) in rats. This model allows for a longitudinal assessment of the physiological changes occurring during the two hypo-gravitational stages of the mission.

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Space Mission Mars Hindlimb Unloading Partial Weight Bearing Rats Ground-based Models Physiological State Astronauts Unloading Levels Behavior Memory Performance Stress Daniela Riveros Research Fellow Laboratory Anesthetized Rat Bench Nose Cone Isoflurane Oxygen Flow Prone Position Pelvic Harness Stainless Steel Chain Swivel Clasp
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