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Journal / Developmental Biology / In Vitro generatie van Somiet derivaten uit…
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Developmental Biology

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JoVE Journal Developmental Biology
In Vitro generatie van Somiet derivaten uit menselijk geïnduceerde pluripotente stamcellen-cellen
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In Vitro generatie van Somiet derivaten uit menselijk geïnduceerde pluripotente stamcellen-cellen

Article DOI: 10.3791/59359-v • 06:21 min • April 25th, 2019
April 25th, 2019 •
1, 2, 2
1Department of Life Science Frontiers, Center for iPS Cells Research and Application, Kyoto University, 2Department of Clinical Application, Center for iPS Cells Research and Application, Kyoto University

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Wij presenteren hier een protocol voor de differentiatie van menselijke geïnduceerde pluripotente stamcellen in elke Somiet derivaat (myotome, sclerotome, dermatoom en syndetome) in chemisch gedefinieerde voorwaarden, die toepassingen heeft in de toekomst ziekte modellering en cel-gebaseerde therapieën in orthopedische chirurgie.

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Ontwikkelingsbiologie kwestie 146 geïnduceerde pluripotente stamcellen differentiatie Paraxiale mesoderm Somiet myotome sclerotome dermatoom syndetome
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